Do you have a manuscript for a science fiction novel ready to submit?
If so, you should know that respected small press Angry Robot has opened the door to un-agented and unsolicited manuscripts until the end of the year. Angry Robot publishes books from an impressive list of up-and-coming (maybe already there?) authors including Aliette de Bodard, Lavie Tadhar, and Matthew Hughes. If you think your completed manuscript has what it takes—and even if you’re not sure—get it into the electronic post. If it’s not under consideration somewhere, it has no chance to be published (unless you’re self-publishing, of course).